STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN21Protein tyrosine phosphatase non-receptor type 21. (1219 aa)    
Predicted Functional Partners:
EIF4E2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
      
 0.601
WWC1
WW and C2 domain containing 1.
    
 
 0.583
SNAP47
Synaptosome associated protein 47.
   
 
 0.564
RALGAPA1
Ral GTPase activating protein catalytic alpha subunit 1.
      
 0.558
MTSS1
MTSS I-BAR domain containing 1.
    
 0.481
PTS
6-pyruvoyltetrahydropterin synthase.
    
 
 0.478
KLHL6
BTB domain-containing protein.
      
 0.454
PHKB
Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family.
      
 0.451
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1.
    
 
 0.439
YAP1
Yes associated protein 1.
   
 
 0.437
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.