STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2012 aa)    
Predicted Functional Partners:
SCN2B
Sodium voltage-gated channel beta subunit 2.
   
 0.862
CACNB4
SH3 domain-containing protein.
   
 0.710
SCN3B
Sodium voltage-gated channel beta subunit 3.
   
 0.638
ANO3
Anoctamin.
      
 0.632
KCNA2
Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family.
   
 
 0.631
PVALB
Parvalbumin; Belongs to the parvalbumin family.
    
 
 0.624
KCNQ2
Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.
   
 0.623
KCNQ3
Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.
   
 0.622
PCDH19
Protocadherin 19.
   
  
 0.612
KCNC1
Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family.
   
 
 0.594
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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