STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPLP00000020285IGv domain-containing protein. (231 aa)    
Predicted Functional Partners:
ICOSLG
Uncharacterized protein.
   
 0.999
CD4
Ig-like domain-containing protein.
  
  
 0.856
CD40LG
CD40 ligand; Belongs to the tumor necrosis factor family.
  
  
 0.849
CD86
CD86 molecule.
  
  
 0.827
CXCR5
C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.811
BCL6
Uncharacterized protein.
      
 0.785
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  
  
 0.782
PDCD1
Ig-like domain-containing protein.
  
  
 0.778
IL21R
Interleukin 21 receptor.
  
  
 0.763
FOXP1
Fork-head domain-containing protein.
   
  
 0.752
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.