FOCAD protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FOCAD

Focadhesin. (1809 aa)

Predicted Functional Partners:

MLLT3

0.625

ENSAPLP00000029609

0.621

PDE8A

0.562

HACD4

0.516

EEFSEC

0.477

TTC37

0.437

EXOSC5

0.430

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEFSEC	FOCAD	ENSAPLP00000016569	ENSAPLP00000020604	Eukaryotic elongation factor, selenocysteine-tRNA specific.	Focadhesin.	0.477
ENSAPLP00000029609	FOCAD	ENSAPLP00000029609	ENSAPLP00000020604	Uncharacterized protein.	Focadhesin.	0.621
ENSAPLP00000029609	PDE8A	ENSAPLP00000029609	ENSAPLP00000003508	Uncharacterized protein.	Phosphodiesterase.	0.636
EXOSC5	FOCAD	ENSAPLP00000023190	ENSAPLP00000020604	Exosome component 5.	Focadhesin.	0.430
EXOSC5	TTC37	ENSAPLP00000023190	ENSAPLP00000004054	Exosome component 5.	Tetratricopeptide repeat domain 37.	0.908
FOCAD	EEFSEC	ENSAPLP00000020604	ENSAPLP00000016569	Focadhesin.	Eukaryotic elongation factor, selenocysteine-tRNA specific.	0.477
FOCAD	ENSAPLP00000029609	ENSAPLP00000020604	ENSAPLP00000029609	Focadhesin.	Uncharacterized protein.	0.621
FOCAD	EXOSC5	ENSAPLP00000020604	ENSAPLP00000023190	Focadhesin.	Exosome component 5.	0.430
FOCAD	HACD4	ENSAPLP00000020604	ENSAPLP00000003016	Focadhesin.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.516
FOCAD	MLLT3	ENSAPLP00000020604	ENSAPLP00000022358	Focadhesin.	MLLT3 super elongation complex subunit.	0.625
FOCAD	PDE8A	ENSAPLP00000020604	ENSAPLP00000003508	Focadhesin.	Phosphodiesterase.	0.562
FOCAD	TTC37	ENSAPLP00000020604	ENSAPLP00000004054	Focadhesin.	Tetratricopeptide repeat domain 37.	0.437
HACD4	FOCAD	ENSAPLP00000003016	ENSAPLP00000020604	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Focadhesin.	0.516
MLLT3	FOCAD	ENSAPLP00000022358	ENSAPLP00000020604	MLLT3 super elongation complex subunit.	Focadhesin.	0.625
PDE8A	ENSAPLP00000029609	ENSAPLP00000003508	ENSAPLP00000029609	Phosphodiesterase.	Uncharacterized protein.	0.636
PDE8A	FOCAD	ENSAPLP00000003508	ENSAPLP00000020604	Phosphodiesterase.	Focadhesin.	0.562
TTC37	EXOSC5	ENSAPLP00000004054	ENSAPLP00000023190	Tetratricopeptide repeat domain 37.	Exosome component 5.	0.908
TTC37	FOCAD	ENSAPLP00000004054	ENSAPLP00000020604	Tetratricopeptide repeat domain 37.	Focadhesin.	0.437