CDC42 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CDC42

Cell division cycle 42. (282 aa)

Predicted Functional Partners:

IQGAP1

0.998

PAK2

0.996

PAK3

0.996

WASL

0.995

PAK6

0.993

U3IGS0_ANAPP

0.986

PARD6A

0.986

PAK1

0.985

PAK4

0.984

PARD6B

0.984

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	IQGAP1	ENSAPLP00000021122	ENSAPLP00000024232	Cell division cycle 42.	IQ motif containing GTPase activating protein 1.	0.998
CDC42	PAK1	ENSAPLP00000021122	ENSAPLP00000019760	Cell division cycle 42.	CRIB domain-containing protein.	0.985
CDC42	PAK2	ENSAPLP00000021122	ENSAPLP00000015359	Cell division cycle 42.	CRIB domain-containing protein.	0.996
CDC42	PAK3	ENSAPLP00000021122	ENSAPLP00000023661	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.996
CDC42	PAK4	ENSAPLP00000021122	ENSAPLP00000017179	Cell division cycle 42.	P21 (RAC1) activated kinase 4.	0.984
CDC42	PAK6	ENSAPLP00000021122	ENSAPLP00000003456	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.993
CDC42	PARD6A	ENSAPLP00000021122	ENSAPLP00000016519	Cell division cycle 42.	Par-6 family cell polarity regulator alpha.	0.986
CDC42	PARD6B	ENSAPLP00000021122	ENSAPLP00000019260	Cell division cycle 42.	Par-6 family cell polarity regulator beta.	0.984
CDC42	U3IGS0_ANAPP	ENSAPLP00000021122	ENSAPLP00000006442	Cell division cycle 42.	Protein kinase domain-containing protein.	0.986
CDC42	WASL	ENSAPLP00000021122	ENSAPLP00000016814	Cell division cycle 42.	WASP like actin nucleation promoting factor.	0.995
IQGAP1	CDC42	ENSAPLP00000024232	ENSAPLP00000021122	IQ motif containing GTPase activating protein 1.	Cell division cycle 42.	0.998
PAK1	CDC42	ENSAPLP00000019760	ENSAPLP00000021122	CRIB domain-containing protein.	Cell division cycle 42.	0.985
PAK1	PAK2	ENSAPLP00000019760	ENSAPLP00000015359	CRIB domain-containing protein.	CRIB domain-containing protein.	0.959
PAK1	PAK3	ENSAPLP00000019760	ENSAPLP00000023661	CRIB domain-containing protein.	Non-specific serine/threonine protein kinase.	0.900
PAK1	PAK4	ENSAPLP00000019760	ENSAPLP00000017179	CRIB domain-containing protein.	P21 (RAC1) activated kinase 4.	0.902
PAK1	PAK6	ENSAPLP00000019760	ENSAPLP00000003456	CRIB domain-containing protein.	Non-specific serine/threonine protein kinase.	0.695
PAK1	U3IGS0_ANAPP	ENSAPLP00000019760	ENSAPLP00000006442	CRIB domain-containing protein.	Protein kinase domain-containing protein.	0.899
PAK1	WASL	ENSAPLP00000019760	ENSAPLP00000016814	CRIB domain-containing protein.	WASP like actin nucleation promoting factor.	0.439
PAK2	CDC42	ENSAPLP00000015359	ENSAPLP00000021122	CRIB domain-containing protein.	Cell division cycle 42.	0.996
PAK2	PAK1	ENSAPLP00000015359	ENSAPLP00000019760	CRIB domain-containing protein.	CRIB domain-containing protein.	0.959