STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (862 aa)    
Predicted Functional Partners:
TXNDC11
Thioredoxin domain-containing protein.
    
 
 0.644
ENSAPLP00000026602
Uncharacterized protein.
    
 
 0.644
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 
 0.572
TXNDC5
Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.
    
 
 0.563
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3.
    
 
 0.505
USP19
Ubiquitin specific peptidase 19.
      
 0.487
ALG2
ALG2 alpha-1,3/1,6-mannosyltransferase.
      
 0.480
ERLEC1
Endoplasmic reticulum lectin 1.
    
 
 0.476
UFD1
Ubiquitin recognition factor in ER associated degradation 1.
      
 0.453
RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
    
 
 0.433
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.