STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNS4SH2 domain-containing protein. (427 aa)    
Predicted Functional Partners:
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.938
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
 
    
 0.903
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.720
ITGB2
Integrin beta.
   
 0.719
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.695
ITGB8
Integrin beta; Belongs to the integrin beta chain family.
   
 0.648
MET
MET proto-oncogene, receptor tyrosine kinase.
   
  0.596
MST1R
Macrophage stimulating 1 receptor.
   
  0.596
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.561
SLC25A48
Solute carrier family 25 member 48; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.542
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.