STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIAM2T cell lymphoma invasion and metastasis 2. (1724 aa)    
Predicted Functional Partners:
ST14
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix.
      
 0.702
TP63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
      
 0.678
DISP3
Dispatched RND transporter family member 3.
      
 0.633
FBXO2
F-box protein 2.
      
 0.632
CDC42
Cell division cycle 42.
    
 0.622
NME3
Nucleoside diphosphate kinase.
    
 
 0.617
ZNF536
Zinc finger protein 536.
      
 0.609
GRIN1
Glutamate ionotropic receptor NMDA type subunit 1.
   
 
 0.590
RAC1
Rac family small GTPase 1.
    
 0.572
RAC3
Rac family small GTPase 3.
    
 0.572
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.