STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YAP1Yes associated protein 1. (444 aa)    
Predicted Functional Partners:
TEAD1
TEA domain transcription factor 1.
   
 0.989
TEAD4
TEA domain transcription factor 4.
   
 0.971
TJP2
Uncharacterized protein; Belongs to the MAGUK family.
   
 0.927
LATS1
Large tumor suppressor kinase 1.
    
 0.924
LATS2
Non-specific serine/threonine protein kinase.
    
 0.919
TP73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
    
 0.823
AMOT
Angiomotin.
    
 0.815
STK3
Serine/threonine kinase 3.
    
 0.800
STK4
Serine/threonine kinase 4.
    
 0.800
SAV1
Salvador family WW domain containing protein 1.
    
 0.768
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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