NOD1 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NOD1

Nucleotide binding oligomerization domain containing 1. (951 aa)

Predicted Functional Partners:

RIPK2

0.992

U3IBK2_ANAPP

0.986

ATG16L1

0.966

SUGT1

0.949

U3J1K3_ANAPP

0.858

CARD9

0.798

TLR4

0.755

RPS27A

0.705

MYD88

0.698

ENSAPLP00000023897

0.693

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG16L1	CARD9	ENSAPLP00000013185	ENSAPLP00000007223	WD_REPEATS_REGION domain-containing protein.	Caspase recruitment domain family member 9.	0.430
ATG16L1	NOD1	ENSAPLP00000013185	ENSAPLP00000023952	WD_REPEATS_REGION domain-containing protein.	Nucleotide binding oligomerization domain containing 1.	0.966
CARD9	ATG16L1	ENSAPLP00000007223	ENSAPLP00000013185	Caspase recruitment domain family member 9.	WD_REPEATS_REGION domain-containing protein.	0.430
CARD9	MYD88	ENSAPLP00000007223	ENSAPLP00000028214	Caspase recruitment domain family member 9.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.687
CARD9	NOD1	ENSAPLP00000007223	ENSAPLP00000023952	Caspase recruitment domain family member 9.	Nucleotide binding oligomerization domain containing 1.	0.798
CARD9	RIPK2	ENSAPLP00000007223	ENSAPLP00000006481	Caspase recruitment domain family member 9.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.449
CARD9	U3J1K3_ANAPP	ENSAPLP00000007223	ENSAPLP00000013380	Caspase recruitment domain family member 9.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.712
ENSAPLP00000023897	MYD88	ENSAPLP00000023897	ENSAPLP00000028214	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.595
ENSAPLP00000023897	NOD1	ENSAPLP00000023897	ENSAPLP00000023952	Uncharacterized protein.	Nucleotide binding oligomerization domain containing 1.	0.693
ENSAPLP00000023897	RIPK2	ENSAPLP00000023897	ENSAPLP00000006481	Uncharacterized protein.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.461
ENSAPLP00000023897	RPS27A	ENSAPLP00000023897	ENSAPLP00000004982	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.997
ENSAPLP00000023897	U3IBK2_ANAPP	ENSAPLP00000023897	ENSAPLP00000004624	Uncharacterized protein.	Uncharacterized protein.	0.461
MYD88	CARD9	ENSAPLP00000028214	ENSAPLP00000007223	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Caspase recruitment domain family member 9.	0.687
MYD88	ENSAPLP00000023897	ENSAPLP00000028214	ENSAPLP00000023897	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Uncharacterized protein.	0.595
MYD88	NOD1	ENSAPLP00000028214	ENSAPLP00000023952	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Nucleotide binding oligomerization domain containing 1.	0.698
MYD88	RIPK2	ENSAPLP00000028214	ENSAPLP00000006481	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.578
MYD88	RPS27A	ENSAPLP00000028214	ENSAPLP00000004982	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Ubiquitin-like domain-containing protein.	0.717
MYD88	TLR4	ENSAPLP00000028214	ENSAPLP00000012401	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor 4.	0.999
MYD88	U3IBK2_ANAPP	ENSAPLP00000028214	ENSAPLP00000004624	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Uncharacterized protein.	0.412
MYD88	U3J1K3_ANAPP	ENSAPLP00000028214	ENSAPLP00000013380	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.783