STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EYA3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (577 aa)    
Predicted Functional Partners:
SIX1
SIX homeobox 1.
   
 
 0.749
TSHB
Thyroid stimulating hormone subunit beta.
      
 0.707
TSHR
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
      
 0.668
CRY1
Cryptochrome circadian regulator 1.
    
 
 0.658
TAC1
Uncharacterized protein.
      
 0.592
ATM
Non-specific serine/threonine protein kinase.
     
 0.578
MRE11
MRE11 homolog, double strand break repair nuclease.
   
 
  0.578
POU1F1
POU domain protein.
   
  
 0.568
SIX4
SIX homeobox 4.
   
 
 0.560
SIX2
SIX homeobox 2.
   
 
 0.560
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.