SIX2 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

SIX2

SIX homeobox 2. (287 aa)

Predicted Functional Partners:

EYA2

0.688

SNTN

0.640

VSTM2A

0.630

EYA4

0.614

ENTPD2

0.609

DACH1

0.603

EYA3

0.560

EYA1

0.560

DLX5

0.525

PAX2

0.519

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DACH1	EYA1	ENSAPLP00000017938	ENSAPLP00000032601	Dachshund family transcription factor 1.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.427
DACH1	EYA2	ENSAPLP00000017938	ENSAPLP00000022684	Dachshund family transcription factor 1.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.506
DACH1	EYA3	ENSAPLP00000017938	ENSAPLP00000024138	Dachshund family transcription factor 1.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.427
DACH1	EYA4	ENSAPLP00000017938	ENSAPLP00000029394	Dachshund family transcription factor 1.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.578
DACH1	SIX2	ENSAPLP00000017938	ENSAPLP00000024293	Dachshund family transcription factor 1.	SIX homeobox 2.	0.603
DLX5	PAX2	ENSAPLP00000023913	ENSAPLP00000014485	Distal-less homeobox 5.	Paired box 2.	0.611
DLX5	SIX2	ENSAPLP00000023913	ENSAPLP00000024293	Distal-less homeobox 5.	SIX homeobox 2.	0.525
ENTPD2	SIX2	ENSAPLP00000004701	ENSAPLP00000024293	Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family.	SIX homeobox 2.	0.609
EYA1	DACH1	ENSAPLP00000032601	ENSAPLP00000017938	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Dachshund family transcription factor 1.	0.427
EYA1	EYA2	ENSAPLP00000032601	ENSAPLP00000022684	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.427
EYA1	EYA3	ENSAPLP00000032601	ENSAPLP00000024138	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.424
EYA1	PAX2	ENSAPLP00000032601	ENSAPLP00000014485	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Paired box 2.	0.438
EYA1	SIX2	ENSAPLP00000032601	ENSAPLP00000024293	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 2.	0.560
EYA2	DACH1	ENSAPLP00000022684	ENSAPLP00000017938	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Dachshund family transcription factor 1.	0.506
EYA2	EYA1	ENSAPLP00000022684	ENSAPLP00000032601	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.427
EYA2	EYA3	ENSAPLP00000022684	ENSAPLP00000024138	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.551
EYA2	EYA4	ENSAPLP00000022684	ENSAPLP00000029394	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.421
EYA2	SIX2	ENSAPLP00000022684	ENSAPLP00000024293	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 2.	0.688
EYA3	DACH1	ENSAPLP00000024138	ENSAPLP00000017938	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Dachshund family transcription factor 1.	0.427
EYA3	EYA1	ENSAPLP00000024138	ENSAPLP00000032601	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.424