STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (358 aa)    
Predicted Functional Partners:
U3I2H1_ANAPP
Uncharacterized protein.
  
 0.971
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
0.944
XRCC3
X-ray repair cross complementing 3.
  
0.925
BRCA2
BRCA2 DNA repair associated.
   
 0.878
FANCM
FA complementation group M.
   
 0.855
RAD51B
RAD51 paralog B.
   
0.852
ENSAPLP00000026881
Zinc-hook domain-containing protein.
  
 0.822
SPO11
SPO11 initiator of meiotic double stranded breaks.
    
 0.821
XRCC2
X-ray repair cross complementing 2.
   
 0.813
RAD52
RAD52 homolog, DNA repair protein.
    
 0.807
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.