node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATN1 | ENSAPLP00000024744 | ENSAPLP00000025412 | ENSAPLP00000024744 | Atrophin 1. | NR LBD domain-containing protein. | 0.573 |
ATN1 | NR2E1 | ENSAPLP00000025412 | ENSAPLP00000026272 | Atrophin 1. | NR LBD domain-containing protein. | 0.573 |
ENSAPLP00000024744 | ATN1 | ENSAPLP00000024744 | ENSAPLP00000025412 | NR LBD domain-containing protein. | Atrophin 1. | 0.573 |
ENSAPLP00000024744 | FOXG1 | ENSAPLP00000024744 | ENSAPLP00000032910 | NR LBD domain-containing protein. | Forkhead box G1. | 0.526 |
ENSAPLP00000024744 | KDM1A | ENSAPLP00000024744 | ENSAPLP00000010903 | NR LBD domain-containing protein. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.517 |
ENSAPLP00000024744 | MED1 | ENSAPLP00000024744 | ENSAPLP00000022023 | NR LBD domain-containing protein. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.484 |
ENSAPLP00000024744 | NCOR1 | ENSAPLP00000024744 | ENSAPLP00000020079 | NR LBD domain-containing protein. | GPS2_interact domain-containing protein. | 0.499 |
ENSAPLP00000024744 | NCOR2 | ENSAPLP00000024744 | ENSAPLP00000013463 | NR LBD domain-containing protein. | Nuclear receptor corepressor 2. | 0.499 |
ENSAPLP00000024744 | NR2E1 | ENSAPLP00000024744 | ENSAPLP00000026272 | NR LBD domain-containing protein. | NR LBD domain-containing protein. | 0.922 |
ENSAPLP00000024744 | RERE | ENSAPLP00000024744 | ENSAPLP00000009307 | NR LBD domain-containing protein. | Arginine-glutamic acid dipeptide repeats. | 0.573 |
ENSAPLP00000024744 | U3IBF2_ANAPP | ENSAPLP00000024744 | ENSAPLP00000004574 | NR LBD domain-containing protein. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.484 |
ENSAPLP00000024744 | U3IIX6_ANAPP | ENSAPLP00000024744 | ENSAPLP00000007198 | NR LBD domain-containing protein. | Uncharacterized protein. | 0.499 |
FOXG1 | ENSAPLP00000024744 | ENSAPLP00000032910 | ENSAPLP00000024744 | Forkhead box G1. | NR LBD domain-containing protein. | 0.526 |
FOXG1 | NR2E1 | ENSAPLP00000032910 | ENSAPLP00000026272 | Forkhead box G1. | NR LBD domain-containing protein. | 0.526 |
KDM1A | ENSAPLP00000024744 | ENSAPLP00000010903 | ENSAPLP00000024744 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | NR LBD domain-containing protein. | 0.517 |
KDM1A | NR2E1 | ENSAPLP00000010903 | ENSAPLP00000026272 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | NR LBD domain-containing protein. | 0.517 |
MED1 | ENSAPLP00000024744 | ENSAPLP00000022023 | ENSAPLP00000024744 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | NR LBD domain-containing protein. | 0.484 |
MED1 | NCOR1 | ENSAPLP00000022023 | ENSAPLP00000020079 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | GPS2_interact domain-containing protein. | 0.471 |
MED1 | NCOR2 | ENSAPLP00000022023 | ENSAPLP00000013463 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 2. | 0.471 |
MED1 | NR2E1 | ENSAPLP00000022023 | ENSAPLP00000026272 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | NR LBD domain-containing protein. | 0.484 |