STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYCNMYCN proto-oncogene, bHLH transcription factor. (445 aa)    
Predicted Functional Partners:
MAX
MYC associated factor X.
    
0.906
MBTPS2
Membrane bound transcription factor peptidase, site 2.
    
 0.717
MXI1
MAX interactor 1, dimerization protein.
    
 0.695
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.694
SCAP
SREBF chaperone.
   
 0.694
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.694
MXD4
MAX dimerization protein 4.
    
 0.693
LTK
Tyrosine-protein kinase receptor.
    
 0.688
ENSAPLP00000032369
Uncharacterized protein.
    
 0.688
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
    
 
 0.684
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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