node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFCAB7 | RSRP1 | ENSAPLP00000014520 | ENSAPLP00000025471 | EF-hand calcium binding domain 7. | Arginine and serine rich protein 1. | 0.586 |
ENSAPLP00000021937 | RSRP1 | ENSAPLP00000021937 | ENSAPLP00000025471 | Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. | Arginine and serine rich protein 1. | 0.518 |
ENSAPLP00000021937 | SYF2 | ENSAPLP00000021937 | ENSAPLP00000026635 | Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. | SYF2 pre-mRNA splicing factor. | 0.431 |
ENSAPLP00000023471 | METTL16 | ENSAPLP00000023471 | ENSAPLP00000022581 | Uncharacterized protein. | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | 0.611 |
ENSAPLP00000023471 | METTL4 | ENSAPLP00000023471 | ENSAPLP00000022760 | Uncharacterized protein. | Methyltransferase like 4; Belongs to the MT-A70-like family. | 0.590 |
ENSAPLP00000023471 | RSRP1 | ENSAPLP00000023471 | ENSAPLP00000025471 | Uncharacterized protein. | Arginine and serine rich protein 1. | 0.558 |
ENSAPLP00000029053 | METTL16 | ENSAPLP00000029053 | ENSAPLP00000022581 | RRM domain-containing protein. | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | 0.431 |
ENSAPLP00000029053 | METTL4 | ENSAPLP00000029053 | ENSAPLP00000022760 | RRM domain-containing protein. | Methyltransferase like 4; Belongs to the MT-A70-like family. | 0.453 |
ENSAPLP00000029053 | RSRP1 | ENSAPLP00000029053 | ENSAPLP00000025471 | RRM domain-containing protein. | Arginine and serine rich protein 1. | 0.605 |
KDM1A | KDM4B | ENSAPLP00000010903 | ENSAPLP00000031693 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine demethylase 4B. | 0.659 |
KDM1A | METTL4 | ENSAPLP00000010903 | ENSAPLP00000022760 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Methyltransferase like 4; Belongs to the MT-A70-like family. | 0.445 |
KDM1A | RSRP1 | ENSAPLP00000010903 | ENSAPLP00000025471 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Arginine and serine rich protein 1. | 0.524 |
KDM4B | KDM1A | ENSAPLP00000031693 | ENSAPLP00000010903 | Lysine demethylase 4B. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.659 |
KDM4B | RSRP1 | ENSAPLP00000031693 | ENSAPLP00000025471 | Lysine demethylase 4B. | Arginine and serine rich protein 1. | 0.586 |
METTL16 | ENSAPLP00000023471 | ENSAPLP00000022581 | ENSAPLP00000023471 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | Uncharacterized protein. | 0.611 |
METTL16 | ENSAPLP00000029053 | ENSAPLP00000022581 | ENSAPLP00000029053 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | RRM domain-containing protein. | 0.431 |
METTL16 | METTL4 | ENSAPLP00000022581 | ENSAPLP00000022760 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | Methyltransferase like 4; Belongs to the MT-A70-like family. | 0.611 |
METTL16 | RSRP1 | ENSAPLP00000022581 | ENSAPLP00000025471 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | Arginine and serine rich protein 1. | 0.625 |
METTL4 | ENSAPLP00000023471 | ENSAPLP00000022760 | ENSAPLP00000023471 | Methyltransferase like 4; Belongs to the MT-A70-like family. | Uncharacterized protein. | 0.590 |
METTL4 | ENSAPLP00000029053 | ENSAPLP00000022760 | ENSAPLP00000029053 | Methyltransferase like 4; Belongs to the MT-A70-like family. | RRM domain-containing protein. | 0.453 |