PTN protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PTN

Pleiotrophin. (186 aa)

Predicted Functional Partners:

ALK

0.956

ENSAPLP00000026147

0.956

PTPRZ1

0.859

LTK

0.826

ENSAPLP00000032369

0.826

PTPRS

0.701

SDC3

0.673

MDK

0.660

ROS1

0.621

MET

0.602

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALK	ENSAPLP00000026147	ENSAPLP00000012833	ENSAPLP00000026147	Tyrosine-protein kinase receptor.	MAM domain-containing protein.	0.894
ALK	ENSAPLP00000032369	ENSAPLP00000012833	ENSAPLP00000032369	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.900
ALK	MDK	ENSAPLP00000012833	ENSAPLP00000015545	Tyrosine-protein kinase receptor.	Midkine.	0.514
ALK	PTN	ENSAPLP00000012833	ENSAPLP00000026081	Tyrosine-protein kinase receptor.	Pleiotrophin.	0.956
ALK	PTPRZ1	ENSAPLP00000012833	ENSAPLP00000022209	Tyrosine-protein kinase receptor.	Protein-tyrosine-phosphatase.	0.411
ENSAPLP00000026147	ALK	ENSAPLP00000026147	ENSAPLP00000012833	MAM domain-containing protein.	Tyrosine-protein kinase receptor.	0.894
ENSAPLP00000026147	ENSAPLP00000032369	ENSAPLP00000026147	ENSAPLP00000032369	MAM domain-containing protein.	Uncharacterized protein.	0.900
ENSAPLP00000026147	LTK	ENSAPLP00000026147	ENSAPLP00000031792	MAM domain-containing protein.	Tyrosine-protein kinase receptor.	0.899
ENSAPLP00000026147	MDK	ENSAPLP00000026147	ENSAPLP00000015545	MAM domain-containing protein.	Midkine.	0.514
ENSAPLP00000026147	PTN	ENSAPLP00000026147	ENSAPLP00000026081	MAM domain-containing protein.	Pleiotrophin.	0.956
ENSAPLP00000026147	PTPRZ1	ENSAPLP00000026147	ENSAPLP00000022209	MAM domain-containing protein.	Protein-tyrosine-phosphatase.	0.411
ENSAPLP00000032369	ALK	ENSAPLP00000032369	ENSAPLP00000012833	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.900
ENSAPLP00000032369	ENSAPLP00000026147	ENSAPLP00000032369	ENSAPLP00000026147	Uncharacterized protein.	MAM domain-containing protein.	0.900
ENSAPLP00000032369	LTK	ENSAPLP00000032369	ENSAPLP00000031792	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.920
ENSAPLP00000032369	MDK	ENSAPLP00000032369	ENSAPLP00000015545	Uncharacterized protein.	Midkine.	0.514
ENSAPLP00000032369	PTN	ENSAPLP00000032369	ENSAPLP00000026081	Uncharacterized protein.	Pleiotrophin.	0.826
ENSAPLP00000032369	PTPRZ1	ENSAPLP00000032369	ENSAPLP00000022209	Uncharacterized protein.	Protein-tyrosine-phosphatase.	0.411
LTK	ENSAPLP00000026147	ENSAPLP00000031792	ENSAPLP00000026147	Tyrosine-protein kinase receptor.	MAM domain-containing protein.	0.899
LTK	ENSAPLP00000032369	ENSAPLP00000031792	ENSAPLP00000032369	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.920
LTK	MDK	ENSAPLP00000031792	ENSAPLP00000015545	Tyrosine-protein kinase receptor.	Midkine.	0.514