STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK2Tyrosine-protein kinase. (1130 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription.
   
 0.993
IFNGR2
Interferon gamma receptor 2.
   
 0.992
SOCS3
Suppressor of cytokine signaling 3.
   
 0.992
STAT1
Signal transducer and activator of transcription.
   
 0.986
STAT4
Signal transducer and activator of transcription.
   
 0.980
ENSAPLP00000024738
Uncharacterized protein.
   
 0.979
LEPR
Leptin receptor.
    
 0.974
ENSAPLP00000032274
Protein kinase domain-containing protein.
   
0.963
IFNGR1
Interferon gamma receptor 1.
    
 0.960
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
 0.959
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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