STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMVKPhosphomevalonate kinase. (188 aa)    
Predicted Functional Partners:
MVK
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
   
 
 0.839
ENSAPLP00000018146
MDD_C domain-containing protein.
   
 
 0.751
DHCR7
7-dehydrocholesterol reductase.
   
 0.731
ENSAPLP00000030953
Nudix hydrolase domain-containing protein.
   
 
 0.674
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
  
 0.647
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
    
 0.625
FDPS
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
   
 
 0.612
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.601
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
  
 0.540
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.485
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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