STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE12Phosphodiesterase 12. (587 aa)    
Predicted Functional Partners:
CNOT1
CCR4-NOT transcription complex subunit 1.
   
 0.818
CNOT9
CCR4-NOT transcription complex subunit 9.
    
 0.816
CNOT2
CCR4-NOT transcription complex subunit 2.
    
 0.812
CNOT4
CCR4-NOT transcription complex subunit 4.
    
 0.800
RNASEL
Uncharacterized protein.
    
 0.744
CNOT8
CCR4-NOT transcription complex subunit 8.
    
 0.731
CNOT7
CCR4-NOT transcription complex subunit 7.
    
 0.731
DDX6
DEAD-box helicase 6; Belongs to the DEAD box helicase family.
    
 0.714
RNGTT
Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.
   
  
 0.713
CDC73
Cell division cycle 73.
   
 
 0.631
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.