STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)    
Predicted Functional Partners:
TANK
TRAF family member associated NFKB activator.
    
 0.999
TBK1
TANK binding kinase 1.
   
 0.999
MAVS
CARD_2 domain-containing protein.
    
 0.998
TRADD
TNFRSF1A associated via death domain.
    
 0.990
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.987
TLR4
Toll like receptor 4.
   
 0.983
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
    
 0.975
TICAM1
TRIF-NTD domain-containing protein.
    
 0.967
U3IBK2_ANAPP
Uncharacterized protein.
   
 0.955
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.955
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.