node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NAT10 | PUS1 | ENSAPLP00000007357 | ENSAPLP00000015554 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | Pseudouridine synthase 1. | 0.464 |
NAT10 | TRMT11 | ENSAPLP00000007357 | ENSAPLP00000001821 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA methyltransferase 11 homolog. | 0.631 |
NAT10 | TRMT6 | ENSAPLP00000007357 | ENSAPLP00000007400 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.589 |
NAT10 | TRMT61A | ENSAPLP00000007357 | ENSAPLP00000011079 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.732 |
NAT10 | TRMT61B | ENSAPLP00000007357 | ENSAPLP00000028974 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA methyltransferase 61B. | 0.685 |
NAT10 | TRUB2 | ENSAPLP00000007357 | ENSAPLP00000024130 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | TruB pseudouridine synthase family member 2. | 0.718 |
NAT10 | TSR1 | ENSAPLP00000007357 | ENSAPLP00000013250 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | TSR1 ribosome maturation factor. | 0.946 |
NAT10 | U3ISD0_ANAPP | ENSAPLP00000007357 | ENSAPLP00000010153 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | Uncharacterized protein. | 0.997 |
NAT10 | WDR4 | ENSAPLP00000007357 | ENSAPLP00000006821 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.521 |
PUS1 | NAT10 | ENSAPLP00000015554 | ENSAPLP00000007357 | Pseudouridine synthase 1. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | 0.464 |
PUS1 | TRMT10C | ENSAPLP00000015554 | ENSAPLP00000011302 | Pseudouridine synthase 1. | tRNA methyltransferase 10C, mitochondrial RNase P subunit. | 0.478 |
PUS1 | TRMT6 | ENSAPLP00000015554 | ENSAPLP00000007400 | Pseudouridine synthase 1. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.592 |
PUS1 | TRMT61A | ENSAPLP00000015554 | ENSAPLP00000011079 | Pseudouridine synthase 1. | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.570 |
PUS1 | TRMT61B | ENSAPLP00000015554 | ENSAPLP00000028974 | Pseudouridine synthase 1. | tRNA methyltransferase 61B. | 0.632 |
PUS1 | TRUB2 | ENSAPLP00000015554 | ENSAPLP00000024130 | Pseudouridine synthase 1. | TruB pseudouridine synthase family member 2. | 0.780 |
PUS1 | U3ISD0_ANAPP | ENSAPLP00000015554 | ENSAPLP00000010153 | Pseudouridine synthase 1. | Uncharacterized protein. | 0.472 |
PUS1 | WDR4 | ENSAPLP00000015554 | ENSAPLP00000006821 | Pseudouridine synthase 1. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.871 |
TRMT10C | PUS1 | ENSAPLP00000011302 | ENSAPLP00000015554 | tRNA methyltransferase 10C, mitochondrial RNase P subunit. | Pseudouridine synthase 1. | 0.478 |
TRMT10C | TRMT11 | ENSAPLP00000011302 | ENSAPLP00000001821 | tRNA methyltransferase 10C, mitochondrial RNase P subunit. | tRNA methyltransferase 11 homolog. | 0.444 |
TRMT10C | TRMT6 | ENSAPLP00000011302 | ENSAPLP00000007400 | tRNA methyltransferase 10C, mitochondrial RNase P subunit. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.793 |