node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BDNF | THRA | ENSAPLP00000032162 | ENSAPLP00000029314 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | Thyroid hormone receptor alpha. | 0.556 |
MED1 | NCOA1 | ENSAPLP00000022023 | ENSAPLP00000013427 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.488 |
MED1 | NCOR1 | ENSAPLP00000022023 | ENSAPLP00000020079 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | GPS2_interact domain-containing protein. | 0.471 |
MED1 | NCOR2 | ENSAPLP00000022023 | ENSAPLP00000013463 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 2. | 0.471 |
MED1 | NR1D2 | ENSAPLP00000022023 | ENSAPLP00000005377 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group D member 2. | 0.714 |
MED1 | RXRA | ENSAPLP00000022023 | ENSAPLP00000012995 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor alpha. | 0.722 |
MED1 | RXRG | ENSAPLP00000022023 | ENSAPLP00000029653 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | NR LBD domain-containing protein. | 0.722 |
MED1 | THRA | ENSAPLP00000022023 | ENSAPLP00000029314 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Thyroid hormone receptor alpha. | 0.541 |
MED1 | U3IIX6_ANAPP | ENSAPLP00000022023 | ENSAPLP00000007198 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Uncharacterized protein. | 0.471 |
NCOA1 | MED1 | ENSAPLP00000013427 | ENSAPLP00000022023 | Nuclear receptor coactivator. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.488 |
NCOA1 | NCOR1 | ENSAPLP00000013427 | ENSAPLP00000020079 | Nuclear receptor coactivator. | GPS2_interact domain-containing protein. | 0.723 |
NCOA1 | NCOR2 | ENSAPLP00000013427 | ENSAPLP00000013463 | Nuclear receptor coactivator. | Nuclear receptor corepressor 2. | 0.596 |
NCOA1 | NR1D2 | ENSAPLP00000013427 | ENSAPLP00000005377 | Nuclear receptor coactivator. | Nuclear receptor subfamily 1 group D member 2. | 0.737 |
NCOA1 | RXRA | ENSAPLP00000013427 | ENSAPLP00000012995 | Nuclear receptor coactivator. | Retinoid X receptor alpha. | 0.953 |
NCOA1 | RXRG | ENSAPLP00000013427 | ENSAPLP00000029653 | Nuclear receptor coactivator. | NR LBD domain-containing protein. | 0.773 |
NCOA1 | THRA | ENSAPLP00000013427 | ENSAPLP00000029314 | Nuclear receptor coactivator. | Thyroid hormone receptor alpha. | 0.555 |
NCOA1 | U3IBF2_ANAPP | ENSAPLP00000013427 | ENSAPLP00000004574 | Nuclear receptor coactivator. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.488 |
NCOA1 | U3IIX6_ANAPP | ENSAPLP00000013427 | ENSAPLP00000007198 | Nuclear receptor coactivator. | Uncharacterized protein. | 0.643 |
NCOR1 | MED1 | ENSAPLP00000020079 | ENSAPLP00000022023 | GPS2_interact domain-containing protein. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.471 |
NCOR1 | NCOA1 | ENSAPLP00000020079 | ENSAPLP00000013427 | GPS2_interact domain-containing protein. | Nuclear receptor coactivator. | 0.723 |