STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAPK15Mitogen-activated protein kinase. (604 aa)    
Predicted Functional Partners:
MAPKAPK2
MAPK activated protein kinase 2.
    
0.714
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
    
0.714
MAP2K3
Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.
   
0.679
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
   
0.679
U3IU71_ANAPP
Protein kinase domain-containing protein.
   
 0.662
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.662
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
   
0.662
CREB5
Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.
    
 0.651
ATF2
Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.
    
 0.651
ATF7
C2H2-type domain-containing protein.
    
 0.651
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.