PAX4 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PAX4

Paired box 4. (222 aa)

Predicted Functional Partners:

TIMM22

0.782

TIMM9

0.686

SUZ12

0.553

INS

0.527

CISD2

0.526

CACTIN

0.526

YY1

0.495

NEUROG1

0.494

NEUROG2

0.494

HNF1A

0.492

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACTIN	PAX4	ENSAPLP00000005018	ENSAPLP00000030875	Cactin, spliceosome C complex subunit.	Paired box 4.	0.526
CACTIN	TIMM9	ENSAPLP00000005018	ENSAPLP00000029671	Cactin, spliceosome C complex subunit.	zf-Tim10_DDP domain-containing protein.	0.774
CISD2	PAX4	ENSAPLP00000000047	ENSAPLP00000030875	CDGSH iron sulfur domain 2.	Paired box 4.	0.526
CISD2	TIMM9	ENSAPLP00000000047	ENSAPLP00000029671	CDGSH iron sulfur domain 2.	zf-Tim10_DDP domain-containing protein.	0.774
HNF1A	INS	ENSAPLP00000002032	ENSAPLP00000012854	Homeobox domain-containing protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.403
HNF1A	PAX4	ENSAPLP00000002032	ENSAPLP00000030875	Homeobox domain-containing protein.	Paired box 4.	0.492
INS	HNF1A	ENSAPLP00000012854	ENSAPLP00000002032	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Homeobox domain-containing protein.	0.403
INS	PAX4	ENSAPLP00000012854	ENSAPLP00000030875	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Paired box 4.	0.527
NEUROG1	PAX4	ENSAPLP00000016861	ENSAPLP00000030875	Neurogenin 1.	Paired box 4.	0.494
NEUROG2	PAX4	ENSAPLP00000031457	ENSAPLP00000030875	Neurogenin 2.	Paired box 4.	0.494
PAX4	CACTIN	ENSAPLP00000030875	ENSAPLP00000005018	Paired box 4.	Cactin, spliceosome C complex subunit.	0.526
PAX4	CISD2	ENSAPLP00000030875	ENSAPLP00000000047	Paired box 4.	CDGSH iron sulfur domain 2.	0.526
PAX4	HNF1A	ENSAPLP00000030875	ENSAPLP00000002032	Paired box 4.	Homeobox domain-containing protein.	0.492
PAX4	INS	ENSAPLP00000030875	ENSAPLP00000012854	Paired box 4.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.527
PAX4	NEUROG1	ENSAPLP00000030875	ENSAPLP00000016861	Paired box 4.	Neurogenin 1.	0.494
PAX4	NEUROG2	ENSAPLP00000030875	ENSAPLP00000031457	Paired box 4.	Neurogenin 2.	0.494
PAX4	SUZ12	ENSAPLP00000030875	ENSAPLP00000021784	Paired box 4.	SUZ12 polycomb repressive complex 2 subunit.	0.553
PAX4	TIMM22	ENSAPLP00000030875	ENSAPLP00000008527	Paired box 4.	Translocase of inner mitochondrial membrane 22.	0.782
PAX4	TIMM9	ENSAPLP00000030875	ENSAPLP00000029671	Paired box 4.	zf-Tim10_DDP domain-containing protein.	0.686
PAX4	YY1	ENSAPLP00000030875	ENSAPLP00000019324	Paired box 4.	YY1 transcription factor.	0.495