ENSAPLP00000031019 protein (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSAPLP00000031019

Uncharacterized protein. (701 aa)

Predicted Functional Partners:

U3J5K7_ANAPP

0.893

U3I8R2_ANAPP

0.735

C3

0.735

ENSAPLP00000030788

0.735

CD59

0.552

SERPING1

0.547

CD109

0.503

SPTAN1

0.503

PIGA

0.499

COPB2

0.497

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3	ENSAPLP00000031019	ENSAPLP00000022526	ENSAPLP00000031019	Complement C3.	Uncharacterized protein.	0.735
CD109	ENSAPLP00000031019	ENSAPLP00000007593	ENSAPLP00000031019	CD109 molecule.	Uncharacterized protein.	0.503
CD59	ENSAPLP00000031019	ENSAPLP00000025224	ENSAPLP00000031019	UPAR/Ly6 domain-containing protein.	Uncharacterized protein.	0.552
COPB2	ENSAPLP00000031019	ENSAPLP00000002388	ENSAPLP00000031019	Coatomer protein complex subunit beta 2.	Uncharacterized protein.	0.497
COPB2	SPTAN1	ENSAPLP00000002388	ENSAPLP00000014910	Coatomer protein complex subunit beta 2.	Spectrin alpha, non-erythrocytic 1.	0.705
ENSAPLP00000030788	ENSAPLP00000031019	ENSAPLP00000030788	ENSAPLP00000031019	NTR domain-containing protein.	Uncharacterized protein.	0.735
ENSAPLP00000031019	C3	ENSAPLP00000031019	ENSAPLP00000022526	Uncharacterized protein.	Complement C3.	0.735
ENSAPLP00000031019	CD109	ENSAPLP00000031019	ENSAPLP00000007593	Uncharacterized protein.	CD109 molecule.	0.503
ENSAPLP00000031019	CD59	ENSAPLP00000031019	ENSAPLP00000025224	Uncharacterized protein.	UPAR/Ly6 domain-containing protein.	0.552
ENSAPLP00000031019	COPB2	ENSAPLP00000031019	ENSAPLP00000002388	Uncharacterized protein.	Coatomer protein complex subunit beta 2.	0.497
ENSAPLP00000031019	ENSAPLP00000030788	ENSAPLP00000031019	ENSAPLP00000030788	Uncharacterized protein.	NTR domain-containing protein.	0.735
ENSAPLP00000031019	PIGA	ENSAPLP00000031019	ENSAPLP00000029180	Uncharacterized protein.	Phosphatidylinositol glycan anchor biosynthesis class A.	0.499
ENSAPLP00000031019	SERPING1	ENSAPLP00000031019	ENSAPLP00000028129	Uncharacterized protein.	Serpin family G member 1; Belongs to the serpin family.	0.547
ENSAPLP00000031019	SPTAN1	ENSAPLP00000031019	ENSAPLP00000014910	Uncharacterized protein.	Spectrin alpha, non-erythrocytic 1.	0.503
ENSAPLP00000031019	U3I8R2_ANAPP	ENSAPLP00000031019	ENSAPLP00000003633	Uncharacterized protein.	Uncharacterized protein.	0.735
ENSAPLP00000031019	U3J5K7_ANAPP	ENSAPLP00000031019	ENSAPLP00000014784	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.893
PIGA	ENSAPLP00000031019	ENSAPLP00000029180	ENSAPLP00000031019	Phosphatidylinositol glycan anchor biosynthesis class A.	Uncharacterized protein.	0.499
SERPING1	ENSAPLP00000031019	ENSAPLP00000028129	ENSAPLP00000031019	Serpin family G member 1; Belongs to the serpin family.	Uncharacterized protein.	0.547
SPTAN1	COPB2	ENSAPLP00000014910	ENSAPLP00000002388	Spectrin alpha, non-erythrocytic 1.	Coatomer protein complex subunit beta 2.	0.705
SPTAN1	ENSAPLP00000031019	ENSAPLP00000014910	ENSAPLP00000031019	Spectrin alpha, non-erythrocytic 1.	Uncharacterized protein.	0.503

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

25

PPI enrichment p-value:

2.6e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006418

tRNA aminoacylation for protein translation

10 of 24

1.76

4.23

5.88e-14

GO:0006520

Cellular amino acid metabolic process

11 of 137

1.05

1.39

6.30e-10

GO:0044271

Cellular nitrogen compound biosynthetic process

11 of 257

0.78

0.8

1.71e-07

GO:0006139

Nucleobase-containing compound metabolic process

11 of 277

0.74

0.75

3.14e-07

GO:1901566

Organonitrogen compound biosynthetic process

11 of 310

0.69

0.67

9.69e-07

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004812

aminoacyl-tRNA ligase activity

10 of 24

1.76

4.29

2.88e-14

GO:0016874

Ligase activity

11 of 72

1.33

2.36

7.81e-13

GO:0002161

aminoacyl-tRNA editing activity

3 of 6

1.84

1.63

0.00042

GO:0005524

ATP binding

11 of 175

0.94

1.13

4.13e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 592

0.41

0.34

0.0027

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:342

tRNA aminoacylation

9 of 16

1.89

4.6

2.65e-13

CL:362

Aminoacyl-tRNA synthetase, class I, conserved site

5 of 5

2.14

3.31

1.28e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pto00970

Aminoacyl-tRNA biosynthesis

10 of 24

1.76

4.4

6.27e-15

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0030

Aminoacyl-tRNA synthetase

10 of 24

1.76

4.37

9.60e-15

KW-0436

Ligase

11 of 62

1.39

2.67

8.61e-14

KW-0648

Protein biosynthesis

8 of 35

1.5

2.59

1.33e-09

KW-0067

ATP-binding

9 of 119

1.02

1.21

2.35e-07

KW-0963

Cytoplasm

6 of 94

0.95

0.83

0.00053

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF08264

Anticodon-binding domain of tRNA ligase

3 of 3

2.14

1.53

0.0012

PF09334

tRNA synthetases class I (M)

3 of 4

2.02

1.49

0.0012

PF03129

Anticodon binding domain

2 of 3

1.97

0.78

0.0334

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR009080

Aminoacyl-tRNA synthetase, class Ia, anticodon-binding

5 of 6

2.07

2.89

8.86e-07

IPR001412

Aminoacyl-tRNA synthetase, class I, conserved site

5 of 6

2.07

2.89

8.86e-07

IPR014729

Rossmann-like alpha/beta/alpha sandwich fold

7 of 29

1.53

2.2

3.86e-07

IPR013155

Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding

3 of 3

2.14

1.61

0.00082

IPR009008

Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain

3 of 3

2.14

1.61

0.00082

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (24%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About