STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1662 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 0.743
SNX29
Sorting nexin 29.
      
 0.716
RIMS4
Regulating synaptic membrane exocytosis 4.
   
  
 0.645
RABIF
RAB interacting factor.
      
 0.586
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
    
 
 0.572
ELMO2
Engulfment and cell motility 2.
      
 0.555
U3I9N3_ANAPP
Uncharacterized protein.
     
 0.549
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.549
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
      
 0.546
RHOG
Ras homolog family member G.
    
 0.534
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.