STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP3Poly [ADP-ribose] polymerase. (729 aa)    
Predicted Functional Partners:
PARP4
Poly [ADP-ribose] polymerase.
     
0.929
U3HZQ3_ANAPP
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.922
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.922
CASP7
Caspase 7; Belongs to the peptidase C14A family.
    
 0.922
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
  
 
0.922
PARG
Poly(ADP-ribose) glycohydrolase.
    
 0.918
APLF
Aprataxin and PNKP like factor.
    
 
 0.807
ADPRHL2
ADP-ribosylhydrolase like 2.
    
 0.777
XRCC6
X-ray repair cross complementing 6.
   
 
 0.767
PARP16
Poly [ADP-ribose] polymerase.
      
 0.749
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.