STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCL1MCL1 apoptosis regulator, BCL2 family member. (325 aa)    
Predicted Functional Partners:
BCL2L11
BCL2 like 11.
    
 0.988
ENSAPLP00000017975
Uncharacterized protein.
    
 0.953
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 0.929
ENSAPLP00000024910
DUF908 domain-containing protein.
    
 
 0.893
BAK1
BCL2 antagonist/killer 1.
    
 
0.890
BMF
Bcl2 modifying factor.
    
 0.851
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 
 0.834
TNKS2
Poly [ADP-ribose] polymerase.
    
 
 0.831
CASP9
Caspase 9; Belongs to the peptidase C14A family.
   
 0.794
BECN1
Uncharacterized protein.
    
 
 0.793
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.