STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRBProtein tyrosine phosphatase receptor type B. (2210 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.918
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.885
MST1R
Macrophage stimulating 1 receptor.
    
 0.885
PLCG1
Phosphoinositide phospholipase C.
    
 0.696
KDR
Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.672
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.648
PTN
Pleiotrophin.
   
 0.591
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
   
  
 0.547
TEK
TEK receptor tyrosine kinase.
   
 0.521
FLT3
Fms related tyrosine kinase 3.
   
 0.462
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.