STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDDC2HD domain containing 2. (268 aa)    
Predicted Functional Partners:
NUDT12
Nudix hydrolase 12.
    
  0.745
NUDT13
Nudix hydrolase 13.
    
  0.738
ADAT2
CMP/dCMP-type deaminase domain-containing protein.
   
 
  0.737
SMUG1
Single-strand-selective monofunctional uracil-DNA glycosylase 1.
   
 
  0.737
PNP
PNP_UDP_1 domain-containing protein.
  
 
  0.655
MTAP
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
  0.655
ENSAPLP00000029383
PNP_UDP_1 domain-containing protein.
  
 
  0.655
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
      
 0.623
DCUN1D3
DCN1-like protein.
   
  
 0.613
FAM172A
Family with sequence similarity 172 member A.
      
 0.551
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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