C12orf66 protein (Anas platyrhynchos) - STRING interaction network

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Score

C12orf66

Chromosome 12 open reading frame 66. (533 aa)

Predicted Functional Partners:

ITFG2

0.997

SZT2

0.995

WDR59

0.973

WDR24

0.972

NPRL2

0.972

DEPDC5

0.924

ENSAPLP00000028801

0.924

BMT2

0.916

NPRL3

0.769

ATAD2B

0.749

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD2B	C12orf66	ENSAPLP00000027769	ENSAPLP00000032221	ATPase family AAA domain containing 2B.	Chromosome 12 open reading frame 66.	0.749
BMT2	C12orf66	ENSAPLP00000012458	ENSAPLP00000032221	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Chromosome 12 open reading frame 66.	0.916
BMT2	DEPDC5	ENSAPLP00000012458	ENSAPLP00000007012	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DEP domain-containing protein.	0.687
BMT2	ENSAPLP00000028801	ENSAPLP00000012458	ENSAPLP00000028801	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Uncharacterized protein.	0.687
BMT2	ITFG2	ENSAPLP00000012458	ENSAPLP00000021825	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Integrin alpha FG-GAP repeat containing 2.	0.884
BMT2	NPRL2	ENSAPLP00000012458	ENSAPLP00000014849	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR2 like, GATOR1 complex subunit.	0.821
BMT2	NPRL3	ENSAPLP00000012458	ENSAPLP00000032869	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR3 like, GATOR1 complex subunit.	0.814
BMT2	SZT2	ENSAPLP00000012458	ENSAPLP00000031096	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Uncharacterized protein.	0.781
BMT2	WDR24	ENSAPLP00000012458	ENSAPLP00000003814	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 24.	0.435
BMT2	WDR59	ENSAPLP00000012458	ENSAPLP00000015619	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 59.	0.430
C12orf66	ATAD2B	ENSAPLP00000032221	ENSAPLP00000027769	Chromosome 12 open reading frame 66.	ATPase family AAA domain containing 2B.	0.749
C12orf66	BMT2	ENSAPLP00000032221	ENSAPLP00000012458	Chromosome 12 open reading frame 66.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.916
C12orf66	DEPDC5	ENSAPLP00000032221	ENSAPLP00000007012	Chromosome 12 open reading frame 66.	DEP domain-containing protein.	0.924
C12orf66	ENSAPLP00000028801	ENSAPLP00000032221	ENSAPLP00000028801	Chromosome 12 open reading frame 66.	Uncharacterized protein.	0.924
C12orf66	ITFG2	ENSAPLP00000032221	ENSAPLP00000021825	Chromosome 12 open reading frame 66.	Integrin alpha FG-GAP repeat containing 2.	0.997
C12orf66	NPRL2	ENSAPLP00000032221	ENSAPLP00000014849	Chromosome 12 open reading frame 66.	NPR2 like, GATOR1 complex subunit.	0.972
C12orf66	NPRL3	ENSAPLP00000032221	ENSAPLP00000032869	Chromosome 12 open reading frame 66.	NPR3 like, GATOR1 complex subunit.	0.769
C12orf66	SZT2	ENSAPLP00000032221	ENSAPLP00000031096	Chromosome 12 open reading frame 66.	Uncharacterized protein.	0.995
C12orf66	WDR24	ENSAPLP00000032221	ENSAPLP00000003814	Chromosome 12 open reading frame 66.	WD repeat domain 24.	0.972
C12orf66	WDR59	ENSAPLP00000032221	ENSAPLP00000015619	Chromosome 12 open reading frame 66.	WD repeat domain 59.	0.973