LIMA1 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LIMA1

LIM domain and actin binding 1. (857 aa)

Predicted Functional Partners:

SIM2

0.632

ZNF410

0.616

PELO

0.548

LRIG3

0.539

CTNNB1

0.499

TMLHE

0.487

ATP1A1

0.466

ENSAPLP00000020742

0.466

GM2A

0.433

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1A1	LIMA1	ENSAPLP00000011162	ENSAPLP00000032562	ATPase Na+/K+ transporting subunit alpha 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	LIM domain and actin binding 1.	0.466
CTNNB1	LIMA1	ENSAPLP00000013346	ENSAPLP00000032562	Catenin beta 1.	LIM domain and actin binding 1.	0.499
ENSAPLP00000020742	LIMA1	ENSAPLP00000020742	ENSAPLP00000032562	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	LIM domain and actin binding 1.	0.466
GM2A	LIMA1	ENSAPLP00000020563	ENSAPLP00000032562	ML domain-containing protein.	LIM domain and actin binding 1.	0.433
GM2A	TMLHE	ENSAPLP00000020563	ENSAPLP00000019112	ML domain-containing protein.	Trimethyllysine hydroxylase, epsilon.	0.611
LIMA1	ATP1A1	ENSAPLP00000032562	ENSAPLP00000011162	LIM domain and actin binding 1.	ATPase Na+/K+ transporting subunit alpha 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.466
LIMA1	CTNNB1	ENSAPLP00000032562	ENSAPLP00000013346	LIM domain and actin binding 1.	Catenin beta 1.	0.499
LIMA1	ENSAPLP00000020742	ENSAPLP00000032562	ENSAPLP00000020742	LIM domain and actin binding 1.	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.466
LIMA1	GM2A	ENSAPLP00000032562	ENSAPLP00000020563	LIM domain and actin binding 1.	ML domain-containing protein.	0.433
LIMA1	LRIG3	ENSAPLP00000032562	ENSAPLP00000028559	LIM domain and actin binding 1.	Leucine rich repeats and immunoglobulin like domains 3.	0.539
LIMA1	PELO	ENSAPLP00000032562	ENSAPLP00000013060	LIM domain and actin binding 1.	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	0.548
LIMA1	SIM2	ENSAPLP00000032562	ENSAPLP00000013878	LIM domain and actin binding 1.	SIM bHLH transcription factor 2.	0.632
LIMA1	TMLHE	ENSAPLP00000032562	ENSAPLP00000019112	LIM domain and actin binding 1.	Trimethyllysine hydroxylase, epsilon.	0.487
LIMA1	ZNF410	ENSAPLP00000032562	ENSAPLP00000013404	LIM domain and actin binding 1.	Zinc finger protein 410.	0.616
LRIG3	LIMA1	ENSAPLP00000028559	ENSAPLP00000032562	Leucine rich repeats and immunoglobulin like domains 3.	LIM domain and actin binding 1.	0.539
PELO	LIMA1	ENSAPLP00000013060	ENSAPLP00000032562	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	LIM domain and actin binding 1.	0.548
PELO	SIM2	ENSAPLP00000013060	ENSAPLP00000013878	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	SIM bHLH transcription factor 2.	0.451
SIM2	LIMA1	ENSAPLP00000013878	ENSAPLP00000032562	SIM bHLH transcription factor 2.	LIM domain and actin binding 1.	0.632
SIM2	PELO	ENSAPLP00000013878	ENSAPLP00000013060	SIM bHLH transcription factor 2.	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	0.451
TMLHE	GM2A	ENSAPLP00000019112	ENSAPLP00000020563	Trimethyllysine hydroxylase, epsilon.	ML domain-containing protein.	0.611