SIAH2 protein (Anas platyrhynchos) - STRING interaction network

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SIAH2

E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (298 aa)

Predicted Functional Partners:

USP13

0.910

CACYBP

0.729

UBE2V2

0.644

U3J5I9_ANAPP

0.621

USP19

0.596

USP5

0.547

SNCA

0.529

ENSAPLP00000028196

0.495

UBE2V1

0.483

SNCAIP

0.461

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACYBP	SIAH2	ENSAPLP00000020909	ENSAPLP00000032642	Calcyclin binding protein.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.729
ENSAPLP00000028196	SIAH2	ENSAPLP00000028196	ENSAPLP00000032642	Gp_dh_C domain-containing protein.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.495
SIAH2	CACYBP	ENSAPLP00000032642	ENSAPLP00000020909	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Calcyclin binding protein.	0.729
SIAH2	ENSAPLP00000028196	ENSAPLP00000032642	ENSAPLP00000028196	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Gp_dh_C domain-containing protein.	0.495
SIAH2	SNCA	ENSAPLP00000032642	ENSAPLP00000028784	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Alpha-synuclein; Belongs to the synuclein family.	0.529
SIAH2	SNCAIP	ENSAPLP00000032642	ENSAPLP00000025763	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Synuclein alpha interacting protein.	0.461
SIAH2	U3J5I9_ANAPP	ENSAPLP00000032642	ENSAPLP00000014766	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.621
SIAH2	UBE2V1	ENSAPLP00000032642	ENSAPLP00000021756	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Ubiquitin conjugating enzyme E2 V1.	0.483
SIAH2	UBE2V2	ENSAPLP00000032642	ENSAPLP00000020539	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Ubiquitin conjugating enzyme E2 V2.	0.644
SIAH2	USP13	ENSAPLP00000032642	ENSAPLP00000011037	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Ubiquitin carboxyl-terminal hydrolase.	0.910
SIAH2	USP19	ENSAPLP00000032642	ENSAPLP00000007325	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Ubiquitin specific peptidase 19.	0.596
SIAH2	USP5	ENSAPLP00000032642	ENSAPLP00000002978	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Ubiquitin carboxyl-terminal hydrolase.	0.547
SNCA	SIAH2	ENSAPLP00000028784	ENSAPLP00000032642	Alpha-synuclein; Belongs to the synuclein family.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.529
SNCA	SNCAIP	ENSAPLP00000028784	ENSAPLP00000025763	Alpha-synuclein; Belongs to the synuclein family.	Synuclein alpha interacting protein.	0.892
SNCAIP	SIAH2	ENSAPLP00000025763	ENSAPLP00000032642	Synuclein alpha interacting protein.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.461
SNCAIP	SNCA	ENSAPLP00000025763	ENSAPLP00000028784	Synuclein alpha interacting protein.	Alpha-synuclein; Belongs to the synuclein family.	0.892
U3J5I9_ANAPP	SIAH2	ENSAPLP00000014766	ENSAPLP00000032642	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.621
U3J5I9_ANAPP	UBE2V1	ENSAPLP00000014766	ENSAPLP00000021756	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme E2 V1.	0.992
U3J5I9_ANAPP	UBE2V2	ENSAPLP00000014766	ENSAPLP00000020539	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme E2 V2.	0.998
UBE2V1	SIAH2	ENSAPLP00000021756	ENSAPLP00000032642	Ubiquitin conjugating enzyme E2 V1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.483

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