STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)    
Predicted Functional Partners:
PAFAH1B2
Platelet activating factor acetylhydrolase 1b catalytic subunit 2.
    
 0.997
NUDC
Nuclear distribution C, dynein complex regulator.
   
 0.973
DYNC1H1
Dynein cytoplasmic 1 heavy chain 1.
   
 0.971
DYNC1I2
Dynein cytoplasmic 1 intermediate chain 2.
   
 0.955
PLA2G7
Platelet-activating factor acetylhydrolase.
     
 0.919
CHPT1
Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
CEPT1
Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
LPCAT2
Lysophosphatidylcholine acyltransferase 2.
     
  0.900
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.896
DCTN3
Dynactin subunit 3.
    
 0.889
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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