STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM12521.1PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase. (808 aa)    
Predicted Functional Partners:
EHM12520.1
PFAM: Vitamin B12 dependent methionine synthase, activation domain.
 
 
 0.978
EHM13282.1
Methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase.
  
 
 0.973
EHM12916.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: Domain of unknown function; domain; 4Fe-4S binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
    
 0.955
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.939
EHM13782.1
Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase.
  
 
 0.937
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.936
fhs
Formyltetrahydrofolate synthetase; PFAM: Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.924
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.913
EHM12668.1
Putative cobalamin binding protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family.
 
 
0.906
EHM13578.1
PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family.
  
 
 0.893
Your Current Organism:
Jonquetella anthropi
NCBI taxonomy Id: 885272
Other names: J. anthropi DSM 22815, Jonquetella anthropi ADV 126, Jonquetella anthropi DSM 22815, Jonquetella anthropi str. DSM 22815, Jonquetella anthropi strain DSM 22815
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