STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGA24822.1Kef-type K+ transport system, membrane component; PFAM: Sodium/hydrogen exchanger family. (393 aa)    
Predicted Functional Partners:
AGA29820.1
Kef-type K+ transport system, predicted NAD-binding component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
0.596
AGA30828.1
Magnesium-translocating P-type ATPase; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; magnesium-translocating P-type ATPase.
  
 
 0.501
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
   
 0.491
AGA27617.1
Sulfate permease-like transporter, MFS superfamily; PFAM: Sulfate transporter family; Carbonic anhydrase.
 
 
 
 0.442
AGA31030.1
PFAM: Mechanosensitive ion channel.
 
   
 0.436
guaB
Inosine-5''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.427
AGA28793.1
PFAM: CBS domain; Voltage gated chloride channel.
     
 0.412
AGA28522.1
Zn-finger-containing protein; PFAM: Zn-finger in ubiquitin-hydrolases and other protein; manually curated; non-canonical start codon.
   
 
 0.402
AGA24821.1
PFAM: Protein of unknown function (DUF1549); Planctomycete cytochrome C; Protein of unknown function (DUF1553).
       0.400
Your Current Organism:
Singulisphaera acidiphila
NCBI taxonomy Id: 886293
Other names: S. acidiphila DSM 18658, Singulisphaera acidiphila DSM 18658, Singulisphaera acidiphila MOB10, Singulisphaera acidiphila str. DSM 18658, Singulisphaera acidiphila strain DSM 18658
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