STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGA26312.1PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. (702 aa)    
Predicted Functional Partners:
AGA26313.1
PFAM: Protein of unknown function (DUF2791).
 
     0.950
AGA26314.1
PglZ domain-containing protein; PFAM: PglZ domain.
 
     0.949
AGA26315.1
Hypothetical protein.
 
     0.949
AGA26318.1
PFAM: Eco57I restriction endonuclease.
 
     0.782
AGA26311.1
Hypothetical protein.
       0.773
AGA26319.1
Nuclease-like protein,protein kinase family protein; PFAM: Protein kinase domain; Nuclease-related domain; Bacterial RNA polymerase, alpha chain C terminal domain.
  
     0.770
AGA26148.1
formamidopyrimidine-DNA glycosylase Fpg; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.627
vapC
Putative nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.418
AGA26176.1
Hypothetical protein.
 
     0.414
AGA29948.1
Putative endonuclease; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
   
    0.410
Your Current Organism:
Singulisphaera acidiphila
NCBI taxonomy Id: 886293
Other names: S. acidiphila DSM 18658, Singulisphaera acidiphila DSM 18658, Singulisphaera acidiphila MOB10, Singulisphaera acidiphila str. DSM 18658, Singulisphaera acidiphila strain DSM 18658
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.