STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGA28688.1Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. (298 aa)    
Predicted Functional Partners:
hypA
Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.983
AGA28678.1
PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
  
 0.930
AGA28677.1
PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF.
 
  
 0.927
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
 
 0.878
ureF-2
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
 
 0.878
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
  
 
 0.856
AGA28679.1
Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.
 
  
 0.844
AGA28676.1
(NiFe) hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF.
 
   
 0.830
AGA28685.1
PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease.
 
   
 0.781
AGA28686.1
Hypothetical protein.
       0.762
Your Current Organism:
Singulisphaera acidiphila
NCBI taxonomy Id: 886293
Other names: S. acidiphila DSM 18658, Singulisphaera acidiphila DSM 18658, Singulisphaera acidiphila MOB10, Singulisphaera acidiphila str. DSM 18658, Singulisphaera acidiphila strain DSM 18658
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.