STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGA29622.1PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain. (909 aa)    
Predicted Functional Partners:
AGA28112.1
UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family.
  
 
 0.926
AGA28593.1
UDP-glucose-4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.926
AGA30640.1
PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1.
 
 
 0.910
AGA27336.1
PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase.
  
  
 0.766
AGA27516.1
Hypothetical protein.
  
 
 0.705
AGA30716.1
Galactose mutarotase-like enzyme; PFAM: Aldose 1-epimerase.
  
 
 0.705
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
  
 0.626
AGA25352.1
Beta-galactosidase/beta-glucuronidase; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; Belongs to the glycosyl hydrolase 2 family.
 
  
 0.588
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.576
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
   
  
 0.519
Your Current Organism:
Singulisphaera acidiphila
NCBI taxonomy Id: 886293
Other names: S. acidiphila DSM 18658, Singulisphaera acidiphila DSM 18658, Singulisphaera acidiphila MOB10, Singulisphaera acidiphila str. DSM 18658, Singulisphaera acidiphila strain DSM 18658
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