node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
YciO_2 | purC | HMPREF0551_0251 | HMPREF0551_0248 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | 0.778 |
YciO_2 | purE | HMPREF0551_0251 | HMPREF0551_0249 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.825 |
YciO_2 | purK | HMPREF0551_0251 | HMPREF0551_0250 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.843 |
purB | purC | HMPREF0551_1628 | HMPREF0551_0248 | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | 0.987 |
purB | purD | HMPREF0551_1628 | HMPREF0551_1480 | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine--glycine ligase; COG: COG0151; Belongs to the GARS family. | 0.887 |
purB | purE | HMPREF0551_1628 | HMPREF0551_0249 | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.837 |
purB | purF | HMPREF0551_1628 | HMPREF0551_1089 | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.895 |
purB | purH | HMPREF0551_1628 | HMPREF0551_0140 | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138. | 0.988 |
purB | purK | HMPREF0551_1628 | HMPREF0551_0250 | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.840 |
purB | purL | HMPREF0551_1628 | HMPREF0551_0701 | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.997 |
purB | purM | HMPREF0551_1628 | HMPREF0551_1561 | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine cyclo-ligase; COG: COG0150. | 0.878 |
purB | purN | HMPREF0551_1628 | HMPREF0551_0361 | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.849 |
purC | YciO_2 | HMPREF0551_0248 | HMPREF0551_0251 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.778 |
purC | purB | HMPREF0551_0248 | HMPREF0551_1628 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.987 |
purC | purD | HMPREF0551_0248 | HMPREF0551_1480 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylamine--glycine ligase; COG: COG0151; Belongs to the GARS family. | 0.997 |
purC | purE | HMPREF0551_0248 | HMPREF0551_0249 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purC | purF | HMPREF0551_0248 | HMPREF0551_1089 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.971 |
purC | purH | HMPREF0551_0248 | HMPREF0551_0140 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138. | 0.969 |
purC | purK | HMPREF0551_0248 | HMPREF0551_0250 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.989 |
purC | purL | HMPREF0551_0248 | HMPREF0551_0701 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |