STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiGlucose-6-phosphate isomerase; COG: COG0166; Belongs to the GPI family. (547 aa)    
Predicted Functional Partners:
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.993
pgm
Phosphoglucomutase, alpha-D-glucose phosphate-specific; COG: COG0033.
 
 0.990
pfkA
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 0.990
pyk
Pyruvate kinase; COG: COG0469; Belongs to the pyruvate kinase family.
 
 
 0.985
tkt
Transketolase; COG: COG0021; Belongs to the transketolase family.
 
 0.982
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.981
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.976
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.970
pgk
Phosphoglycerate kinase; COG: COG0126; Belongs to the phosphoglycerate kinase family.
 
 
 0.963
AlgA
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.951
Your Current Organism:
Lautropia mirabilis
NCBI taxonomy Id: 887898
Other names: L. mirabilis ATCC 51599, Lautropia mirabilis ATCC 51599, Lautropia mirabilis str. ATCC 51599, Lautropia mirabilis strain ATCC 51599
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