node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFV94786.1 | tsaD | HMPREF0551_1533 | HMPREF0551_1530 | Hydrolase, P-loop family; COG: COG0802. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.872 |
EFV94786.1 | yeaZ | HMPREF0551_1533 | HMPREF0551_0757 | Hydrolase, P-loop family; COG: COG0802. | Universal bacterial protein YeaZ. | 0.967 |
YciO_1 | tsaD | HMPREF0551_1068 | HMPREF0551_1530 | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Belongs to the SUA5 family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.613 |
YciO_2 | tsaD | HMPREF0551_0251 | HMPREF0551_1530 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.613 |
aroB | tsaD | HMPREF0551_1865 | HMPREF0551_1530 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.611 |
dnaG | pheS | HMPREF0551_1525 | HMPREF0551_0810 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | phenylalanine--tRNA ligase, alpha subunit; COG: COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.478 |
dnaG | pheT | HMPREF0551_1525 | HMPREF0551_0809 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.632 |
dnaG | tsaD | HMPREF0551_1525 | HMPREF0551_1530 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.637 |
ksgA | pheT | HMPREF0551_0147 | HMPREF0551_0809 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.526 |
ksgA | tsaD | HMPREF0551_0147 | HMPREF0551_1530 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.605 |
pheS | dnaG | HMPREF0551_0810 | HMPREF0551_1525 | phenylalanine--tRNA ligase, alpha subunit; COG: COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.478 |
pheS | pheT | HMPREF0551_0810 | HMPREF0551_0809 | phenylalanine--tRNA ligase, alpha subunit; COG: COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.999 |
pheS | tsaD | HMPREF0551_0810 | HMPREF0551_1530 | phenylalanine--tRNA ligase, alpha subunit; COG: COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.617 |
pheT | dnaG | HMPREF0551_0809 | HMPREF0551_1525 | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.632 |
pheT | ksgA | HMPREF0551_0809 | HMPREF0551_0147 | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.526 |
pheT | pheS | HMPREF0551_0809 | HMPREF0551_0810 | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | phenylalanine--tRNA ligase, alpha subunit; COG: COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.999 |
pheT | ppa | HMPREF0551_0809 | HMPREF0551_1009 | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.527 |
pheT | tsaD | HMPREF0551_0809 | HMPREF0551_1530 | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.598 |
ppa | pheT | HMPREF0551_1009 | HMPREF0551_0809 | Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.527 |
ppa | tsaD | HMPREF0551_1009 | HMPREF0551_1530 | Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.687 |