node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AlgA | EFV95647.1 | HMPREF0551_1432 | HMPREF0551_0555 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family. | Kinase, PfkB family; COG: COG0524. | 0.943 |
AlgA | glmM | HMPREF0551_1432 | HMPREF0551_1317 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.618 |
AlgA | glmS | HMPREF0551_1432 | HMPREF0551_2316 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.920 |
AlgA | glmU | HMPREF0551_1432 | HMPREF0551_2317 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.518 |
AlgA | pgi | HMPREF0551_1432 | HMPREF0551_1366 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucose-6-phosphate isomerase; COG: COG0166; Belongs to the GPI family. | 0.951 |
EFV95647.1 | AlgA | HMPREF0551_0555 | HMPREF0551_1432 | Kinase, PfkB family; COG: COG0524. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.943 |
EFV95647.1 | GltB | HMPREF0551_0555 | HMPREF0551_1863 | Kinase, PfkB family; COG: COG0524. | Class II glutamine amidotransferase; COG: COG0069. | 0.435 |
EFV95647.1 | glmS | HMPREF0551_0555 | HMPREF0551_2316 | Kinase, PfkB family; COG: COG0524. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.911 |
EFV95647.1 | pgi | HMPREF0551_0555 | HMPREF0551_1366 | Kinase, PfkB family; COG: COG0524. | Glucose-6-phosphate isomerase; COG: COG0166; Belongs to the GPI family. | 0.921 |
GltB | EFV95647.1 | HMPREF0551_1863 | HMPREF0551_0555 | Class II glutamine amidotransferase; COG: COG0069. | Kinase, PfkB family; COG: COG0524. | 0.435 |
GltB | GltD | HMPREF0551_1863 | HMPREF0551_1862 | Class II glutamine amidotransferase; COG: COG0069. | Pyridine nucleotide-disulfide oxidoreductase; COG: COG0493. | 0.999 |
GltB | carA | HMPREF0551_1863 | HMPREF0551_1326 | Class II glutamine amidotransferase; COG: COG0069. | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | 0.921 |
GltB | carB | HMPREF0551_1863 | HMPREF0551_1325 | Class II glutamine amidotransferase; COG: COG0069. | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | 0.963 |
GltB | glmS | HMPREF0551_1863 | HMPREF0551_2316 | Class II glutamine amidotransferase; COG: COG0069. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.955 |
GltB | purF | HMPREF0551_1863 | HMPREF0551_1089 | Class II glutamine amidotransferase; COG: COG0069. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.951 |
GltD | GltB | HMPREF0551_1862 | HMPREF0551_1863 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG0493. | Class II glutamine amidotransferase; COG: COG0069. | 0.999 |
GltD | carA | HMPREF0551_1862 | HMPREF0551_1326 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG0493. | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | 0.905 |
GltD | carB | HMPREF0551_1862 | HMPREF0551_1325 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG0493. | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | 0.917 |
GltD | glmS | HMPREF0551_1862 | HMPREF0551_2316 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG0493. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.919 |
GltD | purF | HMPREF0551_1862 | HMPREF0551_1089 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG0493. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.916 |