node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFV01106.1 | EFV01630.1 | HMP0721_1845 | HMP0721_1023 | Single-strand binding family protein; COG: COG0629. | HRDC domain protein. | 0.614 |
EFV01106.1 | polA | HMP0721_1845 | HMP0721_0482 | Single-strand binding family protein; COG: COG0629. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.630 |
EFV01106.1 | recA | HMP0721_1845 | HMP0721_0750 | Single-strand binding family protein; COG: COG0629. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.422 |
EFV01106.1 | rpsB | HMP0721_1845 | HMP0721_0726 | Single-strand binding family protein; COG: COG0629. | Ribosomal protein S2; COG: COG0052; Belongs to the universal ribosomal protein uS2 family. | 0.671 |
EFV01106.1 | topA | HMP0721_1845 | HMP0721_0729 | Single-strand binding family protein; COG: COG0629. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.995 |
EFV01630.1 | EFV01106.1 | HMP0721_1023 | HMP0721_1845 | HRDC domain protein. | Single-strand binding family protein; COG: COG0629. | 0.614 |
EFV01630.1 | polA | HMP0721_1023 | HMP0721_0482 | HRDC domain protein. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.997 |
EFV01630.1 | recA | HMP0721_1023 | HMP0721_0750 | HRDC domain protein. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.979 |
EFV01630.1 | topA | HMP0721_1023 | HMP0721_0729 | HRDC domain protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.999 |
hslU | hslV | HMP0721_0727 | HMP0721_0728 | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.999 |
hslU | rpsB | HMP0721_0727 | HMP0721_0726 | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | Ribosomal protein S2; COG: COG0052; Belongs to the universal ribosomal protein uS2 family. | 0.591 |
hslU | topA | HMP0721_0727 | HMP0721_0729 | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.878 |
hslV | hslU | HMP0721_0728 | HMP0721_0727 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | 0.999 |
hslV | rpsB | HMP0721_0728 | HMP0721_0726 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | Ribosomal protein S2; COG: COG0052; Belongs to the universal ribosomal protein uS2 family. | 0.592 |
hslV | topA | HMP0721_0728 | HMP0721_0729 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.857 |
leuS | nifJ | HMP0721_0787 | HMP0721_0532 | leucine--tRNA ligase; COG: COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | Pyruvate synthase; COG: COG0674. | 0.748 |
leuS | nifJ-2 | HMP0721_0787 | HMP0721_1908 | leucine--tRNA ligase; COG: COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | Pyruvate synthase; COG: COG0674. | 0.732 |
leuS | polA | HMP0721_0787 | HMP0721_0482 | leucine--tRNA ligase; COG: COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.627 |
leuS | recA | HMP0721_0787 | HMP0721_0750 | leucine--tRNA ligase; COG: COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.530 |
leuS | rpsB | HMP0721_0787 | HMP0721_0726 | leucine--tRNA ligase; COG: COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | Ribosomal protein S2; COG: COG0052; Belongs to the universal ribosomal protein uS2 family. | 0.501 |