node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFV01349.1 | argB | HMP0721_1730 | HMP0721_0760 | ABC transporter, substrate-binding protein, family 3; COG: COG0834. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.532 |
EFV01349.1 | argC | HMP0721_1730 | HMP0721_0762 | ABC transporter, substrate-binding protein, family 3; COG: COG0834. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.538 |
EFV01349.1 | argF | HMP0721_1730 | HMP0721_0452 | ABC transporter, substrate-binding protein, family 3; COG: COG0834. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.466 |
EFV01349.1 | argG | HMP0721_1730 | HMP0721_0763 | ABC transporter, substrate-binding protein, family 3; COG: COG0834. | Argininosuccinate synthase; COG: COG0137; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.886 |
EFV01349.1 | argH | HMP0721_1730 | HMP0721_0764 | ABC transporter, substrate-binding protein, family 3; COG: COG0834. | Argininosuccinate lyase; COG: COG0165. | 0.883 |
EFV01349.1 | argJ | HMP0721_1730 | HMP0721_0761 | ABC transporter, substrate-binding protein, family 3; COG: COG0834. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.568 |
EFV01349.1 | argR | HMP0721_1730 | HMP0721_1099 | ABC transporter, substrate-binding protein, family 3; COG: COG0834. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.461 |
argB | EFV01349.1 | HMP0721_0760 | HMP0721_1730 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | ABC transporter, substrate-binding protein, family 3; COG: COG0834. | 0.532 |
argB | argC | HMP0721_0760 | HMP0721_0762 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
argB | argD | HMP0721_0760 | HMP0721_0759 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Aminotransferase, acetylornithine/succinylornithine family; COG: COG4992; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.999 |
argB | argF | HMP0721_0760 | HMP0721_0452 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.978 |
argB | argG | HMP0721_0760 | HMP0721_0763 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Argininosuccinate synthase; COG: COG0137; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.977 |
argB | argH | HMP0721_0760 | HMP0721_0764 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Argininosuccinate lyase; COG: COG0165. | 0.988 |
argB | argJ | HMP0721_0760 | HMP0721_0761 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
argB | argR | HMP0721_0760 | HMP0721_1099 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.891 |
argC | EFV01349.1 | HMP0721_0762 | HMP0721_1730 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | ABC transporter, substrate-binding protein, family 3; COG: COG0834. | 0.538 |
argC | argB | HMP0721_0762 | HMP0721_0760 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.999 |
argC | argD | HMP0721_0762 | HMP0721_0759 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Aminotransferase, acetylornithine/succinylornithine family; COG: COG4992; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.999 |
argC | argF | HMP0721_0762 | HMP0721_0452 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.965 |
argC | argG | HMP0721_0762 | HMP0721_0763 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Argininosuccinate synthase; COG: COG0137; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.979 |