node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFV00550.1 | EFV00551.1 | HMP0721_2367 | HMP0721_2368 | Putative aspartate kinase, monofunctional class; COG: COG0527; Belongs to the aspartokinase family. | ACT domain protein; COG: COG0527. | 0.881 |
EFV00550.1 | asd | HMP0721_2367 | HMP0721_2363 | Putative aspartate kinase, monofunctional class; COG: COG0527; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; COG: COG0136; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.971 |
EFV00550.1 | dapA | HMP0721_2367 | HMP0721_2364 | Putative aspartate kinase, monofunctional class; COG: COG0527; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.758 |
EFV00550.1 | dapB | HMP0721_2367 | HMP0721_2365 | Putative aspartate kinase, monofunctional class; COG: COG0527; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.789 |
EFV00550.1 | dapD | HMP0721_2367 | HMP0721_2366 | Putative aspartate kinase, monofunctional class; COG: COG0527; Belongs to the aspartokinase family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.711 |
EFV00550.1 | dapF | HMP0721_2367 | HMP0721_0777 | Putative aspartate kinase, monofunctional class; COG: COG0527; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.549 |
EFV00550.1 | lysA | HMP0721_2367 | HMP0721_1054 | Putative aspartate kinase, monofunctional class; COG: COG0527; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.958 |
EFV00551.1 | EFV00550.1 | HMP0721_2368 | HMP0721_2367 | ACT domain protein; COG: COG0527. | Putative aspartate kinase, monofunctional class; COG: COG0527; Belongs to the aspartokinase family. | 0.881 |
EFV00551.1 | asd | HMP0721_2368 | HMP0721_2363 | ACT domain protein; COG: COG0527. | Aspartate-semialdehyde dehydrogenase; COG: COG0136; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.939 |
EFV00551.1 | dapA | HMP0721_2368 | HMP0721_2364 | ACT domain protein; COG: COG0527. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.673 |
EFV00551.1 | dapB | HMP0721_2368 | HMP0721_2365 | ACT domain protein; COG: COG0527. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.753 |
EFV00551.1 | dapD | HMP0721_2368 | HMP0721_2366 | ACT domain protein; COG: COG0527. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.667 |
EFV00551.1 | dapF | HMP0721_2368 | HMP0721_0777 | ACT domain protein; COG: COG0527. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.449 |
EFV00551.1 | lysA | HMP0721_2368 | HMP0721_1054 | ACT domain protein; COG: COG0527. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.603 |
EFV00725.1 | asd | HMP0721_2174 | HMP0721_2363 | Dihydrodipicolinate synthetase family; COG: COG0329; Belongs to the DapA family. | Aspartate-semialdehyde dehydrogenase; COG: COG0136; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.869 |
EFV00725.1 | dapA | HMP0721_2174 | HMP0721_2364 | Dihydrodipicolinate synthetase family; COG: COG0329; Belongs to the DapA family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.715 |
EFV00725.1 | dapB | HMP0721_2174 | HMP0721_2365 | Dihydrodipicolinate synthetase family; COG: COG0329; Belongs to the DapA family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.935 |
EFV00725.1 | dapD | HMP0721_2174 | HMP0721_2366 | Dihydrodipicolinate synthetase family; COG: COG0329; Belongs to the DapA family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.484 |
EFV00725.1 | dapF | HMP0721_2174 | HMP0721_0777 | Dihydrodipicolinate synthetase family; COG: COG0329; Belongs to the DapA family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.491 |
EFV00725.1 | lysA | HMP0721_2174 | HMP0721_1054 | Dihydrodipicolinate synthetase family; COG: COG0329; Belongs to the DapA family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.548 |