STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENO18764.1Hypothetical protein; COG: COG0737; Belongs to the 5'-nucleotidase family. (751 aa)    
Predicted Functional Partners:
ENO18765.1
Hypothetical protein; COG: COG2374.
  
 0.998
guaB
IMP dehydrogenase; COG: COG0516.
    
 0.963
guaB2
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.954
deoD
Purine nucleoside phosphorylase; COG: COG0813.
    
  0.949
nudC
NAD(+) diphosphatase; COG: COG2816.
    
  0.948
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.928
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
  0.920
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.918
pyn
Pyrimidine-nucleoside phosphorylase; COG: COG0213.
    
  0.917
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.907
Your Current Organism:
Schaalia cardiffensis
NCBI taxonomy Id: 888050
Other names: Actinomyces cardiffensis F0333, S. cardiffensis F0333, Schaalia cardiffensis F0333
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