node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENO18289.1 | ENO18298.1 | HMPREF9004_0858 | HMPREF9004_0867 | Hypothetical protein. | Endoribonuclease L-PSP family protein; COG: COG0251. | 0.467 |
ENO18289.1 | aroC | HMPREF9004_0858 | HMPREF9004_1372 | Hypothetical protein. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.961 |
ENO18289.1 | guaA | HMPREF9004_0858 | HMPREF9004_1942 | Hypothetical protein. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.839 |
ENO18289.1 | ilvE | HMPREF9004_0858 | HMPREF9004_1755 | Hypothetical protein. | Branched-chain-amino-acid transaminase; COG: COG0115. | 0.956 |
ENO18289.1 | nadE | HMPREF9004_0858 | HMPREF9004_0418 | Hypothetical protein. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.661 |
ENO18289.1 | pncA | HMPREF9004_0858 | HMPREF9004_1964 | Hypothetical protein. | Pyrazinamidase/nicotinamidase; COG: COG1335. | 0.451 |
ENO18298.1 | ENO18289.1 | HMPREF9004_0867 | HMPREF9004_0858 | Endoribonuclease L-PSP family protein; COG: COG0251. | Hypothetical protein. | 0.467 |
ENO18298.1 | aroC | HMPREF9004_0867 | HMPREF9004_1372 | Endoribonuclease L-PSP family protein; COG: COG0251. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.448 |
ENO18298.1 | fusA | HMPREF9004_0867 | HMPREF9004_0525 | Endoribonuclease L-PSP family protein; COG: COG0251. | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.943 |
ENO18298.1 | guaA | HMPREF9004_0867 | HMPREF9004_1942 | Endoribonuclease L-PSP family protein; COG: COG0251. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.483 |
ENO18298.1 | ilvA | HMPREF9004_0867 | HMPREF9004_1611 | Endoribonuclease L-PSP family protein; COG: COG0251. | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.530 |
ENO18298.1 | ilvE | HMPREF9004_0867 | HMPREF9004_1755 | Endoribonuclease L-PSP family protein; COG: COG0251. | Branched-chain-amino-acid transaminase; COG: COG0115. | 0.522 |
ENO18298.1 | nadE | HMPREF9004_0867 | HMPREF9004_0418 | Endoribonuclease L-PSP family protein; COG: COG0251. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.449 |
ENO18298.1 | pncA | HMPREF9004_0867 | HMPREF9004_1964 | Endoribonuclease L-PSP family protein; COG: COG0251. | Pyrazinamidase/nicotinamidase; COG: COG1335. | 0.484 |
ENO18298.1 | pta | HMPREF9004_0867 | HMPREF9004_0412 | Endoribonuclease L-PSP family protein; COG: COG0251. | Phosphate acetyltransferase; COG: COG0280. | 0.785 |
ENO18298.1 | rph | HMPREF9004_0867 | HMPREF9004_1826 | Endoribonuclease L-PSP family protein; COG: COG0251. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.684 |
aroC | ENO18289.1 | HMPREF9004_1372 | HMPREF9004_0858 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Hypothetical protein. | 0.961 |
aroC | ENO18298.1 | HMPREF9004_1372 | HMPREF9004_0867 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Endoribonuclease L-PSP family protein; COG: COG0251. | 0.448 |
aroC | guaA | HMPREF9004_1372 | HMPREF9004_1942 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.455 |
aroC | ilvE | HMPREF9004_1372 | HMPREF9004_1755 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Branched-chain-amino-acid transaminase; COG: COG0115. | 0.587 |