STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plsYAcyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (225 aa)    
Predicted Functional Partners:
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
 0.985
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
  
 0.984
nifJ
Pyruvate synthase; COG: COG0674.
 
  
  0.967
EFU74965.1
Acyltransferase; COG: COG0204.
  
 
 0.966
ppx2
FAD dependent oxidoreductase; COG: COG0578.
     
 0.911
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
    
 0.911
pyk
Pyruvate kinase; COG: COG0469; Belongs to the pyruvate kinase family.
     
 0.806
parE
DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
     
 0.792
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
     
 0.792
pflB
Formate C-acetyltransferase; COG: COG1882.
    
 0.764
Your Current Organism:
Enterococcus italicus
NCBI taxonomy Id: 888064
Other names: E. italicus DSM 15952, Enterococcus italicus DSM 15952, Enterococcus italicus LMG 22039, Enterococcus italicus TP1.5, Enterococcus italicus str. DSM 15952, Enterococcus italicus strain DSM 15952
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